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Biophysical studies of cholesterol effects on chromatin

Changes in chromatin structure regulate gene expression and genome maintenance. Molecules that bind to the nucleosome, the complex of DNA and histone proteins, are key modulators of chromatin structure. Previous work indicated that cholesterol, a ubiquitous cellular lipid, may bind to chromatin in v...

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Detalles Bibliográficos
Autores principales: Silva, Isabel T. G., Fernandes, Vinícius, Souza, Caio, Treptow, Werner, Santos, Guilherme M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Biochemistry and Molecular Biology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5408612/
https://www.ncbi.nlm.nih.gov/pubmed/28331000
http://dx.doi.org/10.1194/jlr.M074997