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Down-regulation of microRNA-216b inhibits IL-1β-induced chondrocyte injury by up-regulation of Smad3

Osteoarthritis (OA) is the most common type of joint disease, leading to a major cause of pain and disability. OA is characterized by the continuous degradation of articular cartilage, mainly resulting in an imbalance between synthesis and degradation of articular chondrocyte extracellular matrix (E...

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Detalles Bibliográficos
Autores principales: He, Jiye, Zhang, Jiahong, Wang, Dongliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5408664/
https://www.ncbi.nlm.nih.gov/pubmed/28356485
http://dx.doi.org/10.1042/BSR20160588