Effect of APOL1 disease risk variants on APOL1 gene product

Gene sequence mutations may alter mRNA transcription, transcript stability, protein translation, protein stability and protein folding. Apolipoprotein L1 (APOL1) has two sets of sequence variants that are risk factors for kidney disease development, APOL1G1 (substitution mutation) and APOL1G2 (delet...

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Detalles Bibliográficos
Autores principales: Haque, Shabirul, Patil, Gauri, Mishra, Abheepsa, Lan, Xiqian, Popik, Waldemar, Malhotra, Ashwani, Skorecki, Karl, Singhal, Pravin C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2017
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5408699/
https://www.ncbi.nlm.nih.gov/pubmed/28385815
http://dx.doi.org/10.1042/BSR20160531

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5408699/
https://www.ncbi.nlm.nih.gov/pubmed/28385815
http://dx.doi.org/10.1042/BSR20160531

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