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Protecting Mammalian Hair Cells from Aminoglycoside-Toxicity: Assessing Phenoxybenzamine’s Potential

Aminoglycosides (AGs) are widely used antibiotics because of their low cost and high efficacy against gram-negative bacterial infection. However, AGs are ototoxic, causing the death of sensory hair cells in the inner ear. Strategies aimed at developing or discovering agents that protect against amin...

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Detalles Bibliográficos
Autores principales: Majumder, Paromita, Moore, Paulette A., Richardson, Guy P., Gale, Jonathan E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5408764/
https://www.ncbi.nlm.nih.gov/pubmed/28503132
http://dx.doi.org/10.3389/fncel.2017.00094