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A Notch positive feedback in the intestinal stem cell niche is essential for stem cell self‐renewal
The intestinal epithelium is the fastest regenerative tissue in the body, fueled by fast‐cycling stem cells. The number and identity of these dividing and migrating stem cells are maintained by a mosaic pattern at the base of the crypt. How the underlying regulatory scheme manages this dynamic stem...
Autores principales: | Chen, Kai‐Yuan, Srinivasan, Tara, Tung, Kuei‐Ling, Belmonte, Julio M, Wang, Lihua, Murthy, Preetish Kadur Lakshminarasimha, Choi, Jiahn, Rakhilin, Nikolai, King, Sarah, Varanko, Anastasia Kristine, Witherspoon, Mavee, Nishimura, Nozomi, Glazier, James A, Lipkin, Steven M, Bu, Pengcheng, Shen, Xiling |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5408779/ https://www.ncbi.nlm.nih.gov/pubmed/28455349 http://dx.doi.org/10.15252/msb.20167324 |
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