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Engineering bacterial thiosulfate and tetrathionate sensors for detecting gut inflammation

There is a groundswell of interest in using genetically engineered sensor bacteria to study gut microbiota pathways, and diagnose or treat associated diseases. Here, we computationally identify the first biological thiosulfate sensor and an improved tetrathionate sensor, both two‐component systems f...

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Detalles Bibliográficos
Autores principales: Daeffler, Kristina N‐M, Galley, Jeffrey D, Sheth, Ravi U, Ortiz‐Velez, Laura C, Bibb, Christopher O, Shroyer, Noah F, Britton, Robert A, Tabor, Jeffrey J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5408782/
https://www.ncbi.nlm.nih.gov/pubmed/28373240
http://dx.doi.org/10.15252/msb.20167416