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State aggregation for fast likelihood computations in molecular evolution
MOTIVATION: Codon models are widely used to identify the signature of selection at the molecular level and to test for changes in selective pressure during the evolution of genes encoding proteins. The large size of the state space of the Markov processes used to model codon evolution makes it diffi...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5408795/ https://www.ncbi.nlm.nih.gov/pubmed/28172542 http://dx.doi.org/10.1093/bioinformatics/btw632 |