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State aggregation for fast likelihood computations in molecular evolution

MOTIVATION: Codon models are widely used to identify the signature of selection at the molecular level and to test for changes in selective pressure during the evolution of genes encoding proteins. The large size of the state space of the Markov processes used to model codon evolution makes it diffi...

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Detalles Bibliográficos
Autores principales: Davydov, Iakov I, Robinson-Rechavi, Marc, Salamin, Nicolas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5408795/
https://www.ncbi.nlm.nih.gov/pubmed/28172542
http://dx.doi.org/10.1093/bioinformatics/btw632