Interference of retroviral envelope with vaccine-induced CD8(+) T cell responses is relieved by co-administration of cytokine-encoding vectors

BACKGROUND: Retroviral envelope (Env) proteins are known to exhibit immunosuppressive properties, which become apparent not only in retroviral infections, but also in gene-based immunizations using retroviral immunogens, where envelope interferes with the induction of CD8(+) T cell responses towards...

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Detalles Bibliográficos
Autores principales: Bongard, Nadine, Lapuente, Dennis, Windmann, Sonja, Dittmer, Ulf, Tenbusch, Matthias, Bayer, Wibke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5408827/
https://www.ncbi.nlm.nih.gov/pubmed/28449719
http://dx.doi.org/10.1186/s12977-017-0352-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5408827/
https://www.ncbi.nlm.nih.gov/pubmed/28449719
http://dx.doi.org/10.1186/s12977-017-0352-7

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