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switchde: inference of switch-like differential expression along single-cell trajectories
MOTIVATION: Pseudotime analyses of single-cell RNA-seq data have become increasingly common. Typically, a latent trajectory corresponding to a biological process of interest—such as differentiation or cell cycle—is discovered. However, relatively little attention has been paid to modelling the diffe...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5408844/ https://www.ncbi.nlm.nih.gov/pubmed/28011787 http://dx.doi.org/10.1093/bioinformatics/btw798 |