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Scater: pre-processing, quality control, normalization and visualization of single-cell RNA-seq data in R

MOTIVATION: Single-cell RNA sequencing (scRNA-seq) is increasingly used to study gene expression at the level of individual cells. However, preparing raw sequence data for further analysis is not a straightforward process. Biases, artifacts and other sources of unwanted variation are present in the...

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Detalles Bibliográficos
Autores principales: McCarthy, Davis J, Campbell, Kieran R, Lun, Aaron T L, Wills, Quin F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5408845/
https://www.ncbi.nlm.nih.gov/pubmed/28088763
http://dx.doi.org/10.1093/bioinformatics/btw777