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Innovations and challenges in detecting long read overlaps: an evaluation of the state-of-the-art

Identifying overlaps between error-prone long reads, specifically those from Oxford Nanopore Technologies (ONT) and Pacific Biosciences (PB), is essential for certain downstream applications, including error correction and de novo assembly. Though akin to the read-to-reference alignment problem, rea...

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Detalles Bibliográficos
Autores principales: Chu, Justin, Mohamadi, Hamid, Warren, René L, Yang, Chen, Birol, Inanç
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5408847/
https://www.ncbi.nlm.nih.gov/pubmed/28003261
http://dx.doi.org/10.1093/bioinformatics/btw811