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Innovations and challenges in detecting long read overlaps: an evaluation of the state-of-the-art
Identifying overlaps between error-prone long reads, specifically those from Oxford Nanopore Technologies (ONT) and Pacific Biosciences (PB), is essential for certain downstream applications, including error correction and de novo assembly. Though akin to the read-to-reference alignment problem, rea...
Autores principales: | Chu, Justin, Mohamadi, Hamid, Warren, René L, Yang, Chen, Birol, Inanç |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5408847/ https://www.ncbi.nlm.nih.gov/pubmed/28003261 http://dx.doi.org/10.1093/bioinformatics/btw811 |
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