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Neutron reflectivity measurement of protein A–antibody complex at the solid-liquid interface

Chromatography is a ubiquitous unit operation in the purification of biopharmaceuticals yet few studies have addressed the biophysical characterisation of proteins at the solution-resin interface. Chromatography and other adsorption and desorption processes have been shown to induce protein aggregat...

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Detalles Bibliográficos
Autores principales: Mazzer, Alice R., Clifton, Luke A., Perevozchikova, Tatiana, Butler, Paul D., Roberts, Christopher J., Bracewell, Daniel G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5408906/
https://www.ncbi.nlm.nih.gov/pubmed/28410804
http://dx.doi.org/10.1016/j.chroma.2017.03.084