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Neutron reflectivity measurement of protein A–antibody complex at the solid-liquid interface
Chromatography is a ubiquitous unit operation in the purification of biopharmaceuticals yet few studies have addressed the biophysical characterisation of proteins at the solution-resin interface. Chromatography and other adsorption and desorption processes have been shown to induce protein aggregat...
Autores principales: | Mazzer, Alice R., Clifton, Luke A., Perevozchikova, Tatiana, Butler, Paul D., Roberts, Christopher J., Bracewell, Daniel G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5408906/ https://www.ncbi.nlm.nih.gov/pubmed/28410804 http://dx.doi.org/10.1016/j.chroma.2017.03.084 |
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