Rapid and Sustained Antidepressant Action of the mGlu2/3 Receptor Antagonist MGS0039 in the Social Defeat Stress Model: Comparison with Ketamine

BACKGROUND: Similar to the N-methyl-D-aspartate receptor antagonist ketamine, the metabotropic glutamate 2/3 receptor antagonist, MGS0039, shows antidepressant effects. However, there are no reports comparing these 2 compounds in the social defeat stress model of depression. METHODS: We examined the...

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Detalles Bibliográficos
Autores principales: Dong, Chao, Zhang, Ji-chun, Yao, Wei, Ren, Qian, Ma, Min, Yang, Chun, Chaki, Shigeyuki, Hashimoto, Kenji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Regular Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5408970/
https://www.ncbi.nlm.nih.gov/pubmed/27765808
http://dx.doi.org/10.1093/ijnp/pyw089

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5408970/
https://www.ncbi.nlm.nih.gov/pubmed/27765808
http://dx.doi.org/10.1093/ijnp/pyw089

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