Cargando…

Rapid and Sustained Antidepressant Action of the mGlu2/3 Receptor Antagonist MGS0039 in the Social Defeat Stress Model: Comparison with Ketamine

BACKGROUND: Similar to the N-methyl-D-aspartate receptor antagonist ketamine, the metabotropic glutamate 2/3 receptor antagonist, MGS0039, shows antidepressant effects. However, there are no reports comparing these 2 compounds in the social defeat stress model of depression. METHODS: We examined the...

Descripción completa

Detalles Bibliográficos
Autores principales:	Dong, Chao, Zhang, Ji-chun, Yao, Wei, Ren, Qian, Ma, Min, Yang, Chun, Chaki, Shigeyuki, Hashimoto, Kenji
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2016
Materias:	Regular Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5408970/ https://www.ncbi.nlm.nih.gov/pubmed/27765808 http://dx.doi.org/10.1093/ijnp/pyw089

Ejemplares similares

On the mechanism of the antidepressant-like action of group II mGlu receptor antagonist, MGS0039
por: Pałucha-Poniewiera, Agnieszka, et al.
Publicado: (2010)

Role of Serotonergic System in the Antidepressant Actions of mGlu2/3 Receptor Antagonists: Similarity to Ketamine
por: Chaki, Shigeyuki, et al.
Publicado: (2019)

Evaluation of the Safety, Tolerability, and Pharmacokinetic Profiles of TP0473292 (TS-161), A Prodrug of a Novel Orthosteric mGlu2/3 Receptor Antagonist TP0178894, in Healthy Subjects and Its Antidepressant-Like Effects in Rodents
por: Watanabe, Mai, et al.
Publicado: (2021)

Role of 5-HT(1A) Receptor Stimulation in the Medial Prefrontal Cortex in the Sustained Antidepressant Effects of Ketamine
por: Fukumoto, Kenichi, et al.
Publicado: (2017)

Group II mGlu receptor antagonist LY341495 enhances the antidepressant-like effects of ketamine in the forced swim test in rats
por: Podkowa, Karolina, et al.
Publicado: (2016)

Comparison of R-ketamine and rapastinel antidepressant effects in the social defeat stress model of depression
por: Yang, Bangkun, et al.
Publicado: (2016)

Structural insights into dimerization and activation of the mGlu2–mGlu3 and mGlu2–mGlu4 heterodimers
por: Wang, Xinwei, et al.
Publicado: (2023)

Lack of metabolism in (R)-ketamine’s antidepressant actions in a chronic social defeat stress model
por: Zhang, Kai, et al.
Publicado: (2018)

Is Metabolism of (R)-Ketamine Essential for the Antidepressant Effects?
por: Chaki, Shigeyuki
Publicado: (2017)

Beyond Ketamine: New Approaches to the Development of Safer Antidepressants
por: Chaki, Shigeyuki
Publicado: (2017)

5-Hydroxytryptamine-Independent Antidepressant Actions of (R)-Ketamine in a Chronic Social Defeat Stress Model
por: Zhang, Kai, et al.
Publicado: (2017)

Author Correction: Lack of metabolism in (R)-ketamine’s antidepressant actions in a chronic social defeat stress model
por: Zhang, Kai, et al.
Publicado: (2018)

No Sex-Specific Differences in the Acute Antidepressant Actions of (R)-Ketamine in an Inflammation Model
por: Chang, Lijia, et al.
Publicado: (2018)

Role of Inflammatory Bone Markers in the Antidepressant Actions of (R)-Ketamine in a Chronic Social Defeat Stress Model
por: Zhang, Kai, et al.
Publicado: (2018)

Possible role of the gut microbiota–brain axis in the antidepressant effects of (R)-ketamine in a social defeat stress model
por: Yang, Chun, et al.
Publicado: (2017)

Vasopressin V(1B) Receptor Antagonists as Potential Antidepressants
por: Chaki, Shigeyuki
Publicado: (2021)

Microglial ERK-NRBP1-CREB-BDNF signaling in sustained antidepressant actions of (R)-ketamine
por: Yao, Wei, et al.
Publicado: (2021)

mGlu2 metabotropic glutamate receptors restrain inflammatory pain and mediate the analgesic activity of dual mGlu2/mGlu3 receptor agonists
por: Zammataro, Magda, et al.
Publicado: (2011)

Correction: Microglial ERK-NRBP1-CREB-BDNF signaling in sustained antidepressant actions of (R)-ketamine
por: Yao, Wei, et al.
Publicado: (2021)

Allosteric Modulators for mGlu Receptors
por: Gasparini, F, et al.
Publicado: (2007)

Improved Syntheses of the mGlu(5) Antagonists MMPEP and MTEP Using Sonogashira Cross-Coupling
por: Mu, Boshuai, et al.
Publicado: (2018)

HCN channel inhibitor induces ketamine-like rapid and sustained antidepressant effects in chronic social defeat stress model
por: Cai, Min, et al.
Publicado: (2023)

Decreased striatal dopamine in group II metabotropic glutamate receptor (mGlu2/mGlu3) double knockout mice
por: Lane, Tracy A, et al.
Publicado: (2013)

Emotional Impairment and Persistent Upregulation of mGlu(5) Receptor following Morphine Abstinence: Implications of an mGlu(5)-MOPr Interaction
por: Zanos, Panos, et al.
Publicado: (2016)

mGlu1 Receptors Monopolize the Synaptic Control of Cerebellar Purkinje Cells by Epigenetically Down-Regulating mGlu5 Receptors
por: Notartomaso, Serena, et al.
Publicado: (2018)

Combined Administration of (R)-Ketamine and the mGlu2/3 Receptor Antagonist LY341495 Induces Rapid and Sustained Effects in the CUMS Model of Depression via a TrkB/BDNF-Dependent Mechanism
por: Rafało-Ulińska, Anna, et al.
Publicado: (2022)

Defeating cancer with antidepressants
por: Lieb, J
Publicado: (2008)

mGlu5 Receptor Functional Interactions and Addiction
por: Brown, Robyn M., et al.
Publicado: (2012)

mGlu(5) Positive Allosteric Modulators Facilitate Long-Term Potentiation via Disinhibition Mediated by mGlu(5)-Endocannabinoid Signaling
por: Xiang, Zixiu, et al.
Publicado: (2019)

Lack of Antidepressant Effects of Low-Voltage-Sensitive T-Type Calcium Channel Blocker Ethosuximide in a Chronic Social Defeat Stress Model: Comparison with (R)-Ketamine
por: Tian, Zheng, et al.
Publicado: (2018)

Effect of Donepezil on Group II mGlu Receptor Agonist- or Antagonist-Induced Amnesia on Passive Avoidance in Mice
por: Sato, Tomoaki, et al.
Publicado: (2003)

Molecular and cellular mechanisms underlying the antidepressant effects of ketamine enantiomers and its metabolites
por: Yang, Chun, et al.
Publicado: (2019)

Neurobiological Insights from mGlu Receptor Allosteric Modulation
por: O’Brien, Daniel E, et al.
Publicado: (2015)

Exploring the Activation Mechanism of the mGlu5 Transmembrane Domain
por: Lans, Isaias, et al.
Publicado: (2020)

Regulation and functional consequences of mGlu(4) RNA editing
por: Hofmann, Christopher S., et al.
Publicado: (2021)

Differential activity of mGlu(7) allosteric modulators provides evidence for mGlu(7/8) heterodimers at hippocampal Schaffer collateral-CA1 synapses
por: Lin, Xin, et al.
Publicado: (2022)

Interaction of hallucinogenic rapid-acting antidepressants with mGlu2/3 receptor ligands as a window for more effective therapies
por: Chruścicka-Smaga, Barbara, et al.
Publicado: (2023)

A BDNF Val66Met Polymorphism and Ketamine-induced Rapid Antidepressant Action
por: Hashimoto, Kenji
Publicado: (2012)

Comparison of (R)-ketamine and lanicemine on depression-like phenotype and abnormal composition of gut microbiota in a social defeat stress model
por: Qu, Youge, et al.
Publicado: (2017)

Antidepressant Effects of (+)-MK-801 and (-)-MK-801 in the Social Defeat Stress Model
por: Yang, Bangkun, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_2kmoahjp0pdb9orkense0d2eaj