S-Ketamine Rapidly Reverses Synaptic and Vascular Deficits of Hippocampus in Genetic Animal Model of Depression

BACKGROUND: The neurovascular plasticity of hippocampus is an important theory underlying major depression. Ketamine as a novel glutamatergic antidepressant drug can induce a rapid antidepressant effect within hours. In a mechanistic proof of this concept, we examined whether ketamine leads to an in...

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Detalles Bibliográficos
Autores principales: Ardalan, Maryam, Wegener, Gregers, Rafati, Ali H., Nyengaard, Jens R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Regular Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5408982/
https://www.ncbi.nlm.nih.gov/pubmed/27815416
http://dx.doi.org/10.1093/ijnp/pyw098

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5408982/
https://www.ncbi.nlm.nih.gov/pubmed/27815416
http://dx.doi.org/10.1093/ijnp/pyw098

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