Increased mitophagy in the skeletal muscle of spinal and bulbar muscular atrophy patients

Spinal and bulbar muscular atrophy (SBMA) is a neuromuscular disorder caused by polyglutamine expansion in the androgen receptor (AR) and characterized by the loss of lower motor neurons. Here we investigated pathological processes occurring in muscle biopsy specimens derived from SBMA patients and,...

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Detalles Bibliográficos
Autores principales: Borgia, Doriana, Malena, Adriana, Spinazzi, Marco, Desbats, Maria Andrea, Salviati, Leonardo, Russell, Aaron P., Miotto, Giovanni, Tosatto, Laura, Pegoraro, Elena, Sorarù, Gianni, Pennuto, Maria, Vergani, Lodovica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5409076/
https://www.ncbi.nlm.nih.gov/pubmed/28087734
http://dx.doi.org/10.1093/hmg/ddx019

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5409076/
https://www.ncbi.nlm.nih.gov/pubmed/28087734
http://dx.doi.org/10.1093/hmg/ddx019

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