Increased NBCn1 expression, Na(+)/ [Formula: see text] co-transport and intracellular pH in human vascular smooth muscle cells with a risk allele for hypertension

Genome-wide association studies have revealed an association between variation at the SLC4A7 locus and blood pressure. SLC4A7 encodes the electroneutral Na(+)/ [Formula: see text] co-transporter NBCn1 which regulates intracellular pH (pH(i)). We conducted a functional study of variants at this locus...

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Detalles Bibliográficos
Autores principales: Ng, Fu Liang, Boedtkjer, Ebbe, Witkowska, Kate, Ren, Meixia, Zhang, Ruoxin, Tucker, Arthur, Aalkjær, Christian, Caulfield, Mark J., Ye, Shu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5409084/
https://www.ncbi.nlm.nih.gov/pubmed/28087731
http://dx.doi.org/10.1093/hmg/ddx015

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5409084/
https://www.ncbi.nlm.nih.gov/pubmed/28087731
http://dx.doi.org/10.1093/hmg/ddx015

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