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PI3K and ERK signaling pathways are involved in differentiation of monocytic cells induced by 27-hydroxycholesterol

27-Hydroxycholesterol induces differentiation of monocytic cells into mature dendritic cells, mDCs. In the current study we sought to determine roles of the PI3K and the ERK pathways in the 27OHChol-induced differentiation. Up-regulation of mDC-specific markers like CD80, CD83 and CD88 induced by st...

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Detalles Bibliográficos
Autores principales: Son, Yonghae, Kim, Bo-Young, Park, Young Chul, Eo, Seong-Kug, Cho, Hyok-rae, Kim, Koanhoi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Physiological Society and The Korean Society of Pharmacology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5409116/
https://www.ncbi.nlm.nih.gov/pubmed/28461772
http://dx.doi.org/10.4196/kjpp.2017.21.3.301