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LC-MS-MS quantitative analysis reveals the association between FTO and DNA methylation

Fat mass and obesity-associated protein (FTO) is α-ketoglutarate-dependent dioxygenase and responsible for demethylating N6-methyladenosine (m6A) in mRNA, 3-methylthymine (m3T) in single-stranded DNA (ssDNA) and 3-methyluracil (m3U) in single-stranded RNA (ssRNA). Its other function remains unknown...

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Detalles Bibliográficos
Autores principales: Zhu, Yuting, Zhou, Guangyu, Yu, Xuebin, Xu, Qiang, Wang, Kai, Xie, Dan, Yang, Qingkai, Wang, Lina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5409144/
https://www.ncbi.nlm.nih.gov/pubmed/28453518
http://dx.doi.org/10.1371/journal.pone.0175849