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Tumor-targeted SN38 inhibits growth of early stage non-small cell lung cancer (NSCLC) in a KRas/p53 transgenic mouse model

Non-small cell lung cancer (NSCLC) is the leading cause of cancer death worldwide, with a 5-year survival of only ~16%. Potential strategies to address NSCLC mortality include improvements in early detection and prevention, and development of new therapies suitable for use in patients with early and...

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Detalles Bibliográficos
Autores principales: Deneka, Alexander Y., Haber, Leora, Kopp, Meghan C., Gaponova, Anna V., Nikonova, Anna S., Golemis, Erica A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5409145/
https://www.ncbi.nlm.nih.gov/pubmed/28453558
http://dx.doi.org/10.1371/journal.pone.0176747