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Tumor-targeted SN38 inhibits growth of early stage non-small cell lung cancer (NSCLC) in a KRas/p53 transgenic mouse model
Non-small cell lung cancer (NSCLC) is the leading cause of cancer death worldwide, with a 5-year survival of only ~16%. Potential strategies to address NSCLC mortality include improvements in early detection and prevention, and development of new therapies suitable for use in patients with early and...
Autores principales: | Deneka, Alexander Y., Haber, Leora, Kopp, Meghan C., Gaponova, Anna V., Nikonova, Anna S., Golemis, Erica A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5409145/ https://www.ncbi.nlm.nih.gov/pubmed/28453558 http://dx.doi.org/10.1371/journal.pone.0176747 |
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