Altered nucleocytoplasmic proteome and transcriptome distributions in an in vitro model of amyotrophic lateral sclerosis

Aberrant nucleocytoplasmic localization of proteins has been implicated in many neurodegenerative diseases. Evidence suggests that cytoplasmic mislocalization of nuclear proteins such as transactive response DNA-binding protein 43 (TDP-43) and fused in sarcoma (FUS) may be associated with neurotoxic...

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Detalles Bibliográficos
Autores principales: Kim, Jee-Eun, Hong, Yoon Ho, Kim, Jin Young, Jeon, Gye Sun, Jung, Jung Hee, Yoon, Byung-Nam, Son, Sung-Yeon, Lee, Kwang-Woo, Kim, Jong-Il, Sung, Jung-Joon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5409181/
https://www.ncbi.nlm.nih.gov/pubmed/28453527
http://dx.doi.org/10.1371/journal.pone.0176462

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5409181/
https://www.ncbi.nlm.nih.gov/pubmed/28453527
http://dx.doi.org/10.1371/journal.pone.0176462

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