Effect of genetic background on the phenotype of the Smn(2B/-) mouse model of spinal muscular atrophy

Spinal muscular atrophy (SMA) is caused by mutations or deletions in the Survival Motor Neuron 1 (SMN1) gene in humans. Modifiers of the SMA symptoms have been identified and genetic background has a substantial effect in the phenotype and survival of the severe mouse model of SMA. Previously, we ge...

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Detalles Bibliográficos
Autores principales: Eshraghi, Mehdi, McFall, Emily, Gibeault, Sabrina, Kothary, Rashmi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5409218/
https://www.ncbi.nlm.nih.gov/pubmed/28172892
http://dx.doi.org/10.1093/hmg/ddw278

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5409218/
https://www.ncbi.nlm.nih.gov/pubmed/28172892
http://dx.doi.org/10.1093/hmg/ddw278

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