Uncoupling the Trade-Off between Somatic Proteostasis and Reproduction in Caenorhabditis elegans Models of Polyglutamine Diseases

Caenorhabditis elegans somatic protein homeostasis (proteostasis) is actively remodeled at the onset of reproduction. This proteostatic collapse is regulated cell-nonautonomously by signals from the reproductive system that transmit the commitment to reproduction to somatic cells. Here, we asked whe...

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Detalles Bibliográficos
Autores principales: Shemesh, Netta, Shai, Nadav, Meshnik, Lana, Katalan, Rotem, Ben-Zvi, Anat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5409330/
https://www.ncbi.nlm.nih.gov/pubmed/28503130
http://dx.doi.org/10.3389/fnmol.2017.00101

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5409330/
https://www.ncbi.nlm.nih.gov/pubmed/28503130
http://dx.doi.org/10.3389/fnmol.2017.00101

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