Hepatocellular Carcinomas Originate Predominantly from Hepatocytes and Benign Lesions from Hepatic Progenitor Cells

Hepatocellular carcinoma (HCC) is an aggressive primary liver cancer. However, its origin remains a debated question. Using human data and various hepatocarcinogenesis mouse models, we show that, in early stages, transformed hepatocytes, independent of their proliferation status, activate hepatic pr...

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Detalles Bibliográficos
Autores principales: Tummala, Krishna S., Brandt, Marta, Teijeiro, Ana, Graña, Osvaldo, Schwabe, Robert F., Perna, Cristian, Djouder, Nabil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5409928/
https://www.ncbi.nlm.nih.gov/pubmed/28423321
http://dx.doi.org/10.1016/j.celrep.2017.03.059

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5409928/
https://www.ncbi.nlm.nih.gov/pubmed/28423321
http://dx.doi.org/10.1016/j.celrep.2017.03.059

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