Longitudinal genomic surveillance of Plasmodium falciparum malaria parasites reveals complex genomic architecture of emerging artemisinin resistance

BACKGROUND: Artemisinin-based combination therapies are the first line of treatment for Plasmodium falciparum infections worldwide, but artemisinin resistance has risen rapidly in Southeast Asia over the past decade. Mutations in the kelch13 gene have been implicated in this resistance. We used long...

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Detalles Bibliográficos
Autores principales: Cerqueira, Gustavo C., Cheeseman, Ian H., Schaffner, Steve F., Nair, Shalini, McDew-White, Marina, Phyo, Aung Pyae, Ashley, Elizabeth A., Melnikov, Alexandre, Rogov, Peter, Birren, Bruce W., Nosten, François, Anderson, Timothy J. C., Neafsey, Daniel E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5410087/
https://www.ncbi.nlm.nih.gov/pubmed/28454557
http://dx.doi.org/10.1186/s13059-017-1204-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5410087/
https://www.ncbi.nlm.nih.gov/pubmed/28454557
http://dx.doi.org/10.1186/s13059-017-1204-4

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