Cargando…

Transcription enhancers as major determinants of SV40 polyomavirus growth efficiency and host cell tropism

The non-coding control region (NCCR) of polyomaviruses includes the promoters for early and late genes, a transcription enhancer and the origin of DNA replication. Particularly virulent variants of the human pathogens BKPyV and JCPyV, as well as of simian virus 40 (SV40), occur in vitro and in vivo....

Descripción completa

Detalles Bibliográficos
Autores principales: Schmidt, Katharina, Keiser, Simon, Günther, Viola, Georgiev, Oleg, Hirsch, Hans H., Schaffner, Walter, Bethge, Tobias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Microbiology Society 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5410105/
https://www.ncbi.nlm.nih.gov/pubmed/27100458
http://dx.doi.org/10.1099/jgv.0.000487