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The stem cell/cancer stem cell marker ALDH1A3 regulates the expression of the survival factor tissue transglutaminase, in mesenchymal glioma stem cells

Tissue transglutaminase (tTG), a dual-function enzyme with GTP-binding and acyltransferase activities, has been implicated in the survival and chemotherapy resistance of aggressive cancer cells and cancer stem cells, including glioma stem cells (GSCs). Using a model system comprising two distinct su...

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Detalles Bibliográficos
Autores principales: Sullivan, Kelly E., Rojas, Kathy, Cerione, Richard A., Nakano, Ichiro, Wilson, Kristin F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5410226/
https://www.ncbi.nlm.nih.gov/pubmed/28423611
http://dx.doi.org/10.18632/oncotarget.16479