Pregnancy at early age is associated with a reduction of progesterone-responsive cells and epithelial Wnt signaling in human breast tissue

BACKGROUND: Pregnancy at early age is the most significant modifiable factor which consistently decreases lifetime breast cancer risk. However, the underlying mechanisms haven't been conclusively identified. Studies in mice suggest a reduction in progesterone-receptor (PR) sensitive epithelial...

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Detalles Bibliográficos
Autores principales: Muenst, Simone, Mechera, Robert, Däster, Silvio, Piscuoglio, Salvatore, Ng, Charlotte K.Y., Meier-Abt, Fabienne, Weber, Walter P., Soysal, Savas D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper: Pathology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5410228/
https://www.ncbi.nlm.nih.gov/pubmed/28423605
http://dx.doi.org/10.18632/oncotarget.16023

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5410228/
https://www.ncbi.nlm.nih.gov/pubmed/28423605
http://dx.doi.org/10.18632/oncotarget.16023

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