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Pregnancy at early age is associated with a reduction of progesterone-responsive cells and epithelial Wnt signaling in human breast tissue
BACKGROUND: Pregnancy at early age is the most significant modifiable factor which consistently decreases lifetime breast cancer risk. However, the underlying mechanisms haven't been conclusively identified. Studies in mice suggest a reduction in progesterone-receptor (PR) sensitive epithelial...
Autores principales: | Muenst, Simone, Mechera, Robert, Däster, Silvio, Piscuoglio, Salvatore, Ng, Charlotte K.Y., Meier-Abt, Fabienne, Weber, Walter P., Soysal, Savas D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5410228/ https://www.ncbi.nlm.nih.gov/pubmed/28423605 http://dx.doi.org/10.18632/oncotarget.16023 |
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