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Stat5 deficiency decreases transcriptional heterogeneity and supports emergence of hematopoietic sub-populations

Aging is associated with significant changes in hematopoiesis, including clonal dominance, anemia, myeloid malignancies, and reduced activation of signal transducer and activator of transcription 5 (Stat5). In previous studies, Stat5 deletion surprisingly amplified FLT3/ITD(+) myeloid expansion or M...

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Detalles Bibliográficos
Autores principales:	Wang, Zhengqi, Bunting, Kevin D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5410237/ https://www.ncbi.nlm.nih.gov/pubmed/28390194 http://dx.doi.org/10.18632/oncotarget.15236

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