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Combination antiretroviral therapy (cART) restores HIV-1 infection-mediated impairment of JAK-STAT signaling pathway

JAK-STAT signaling pathway has a crucial role in host innate immunity against viral infections, including HIV-1. We therefore examined the impact of HIV-1 infection and combination antiretroviral therapy (cART) on JAK-STAT signaling pathway. Compared to age-matched healthy donors (n = 18), HIV-1-inf...

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Detalles Bibliográficos
Autores principales: Liu, Man-Qing, Zhao, Min, Kong, Wen-Hua, Tang, Li, Wang, Fang, Zhu, Ze-Rong, Wang, Xia, Qiu, Hong-Yan, Zhou, Dun-Jin, Wang, Xu, Ho, Wen-Zhe, Zhou, Wang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5410242/
https://www.ncbi.nlm.nih.gov/pubmed/28186978
http://dx.doi.org/10.18632/oncotarget.15121