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Clinicopathological signature of p21-activated kinase 1 in prostate cancer and its regulation of proliferation and autophagy via the mTOR signaling pathway

Prostate cancer (PCa) is one of the most common malignant tumors in men. The etiology and pathogenesis of PCa remain unclear. P21-activated kinase 1 (PAK1) is a member of a family of serine/threonine kinases and regulates cell growth and contributes to tumor invasion and metastasis. However, the ass...

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Detalles Bibliográficos
Autores principales: Wang, Zhanyu, Jia, Guojin, Li, Yan, Liu, Jikai, Luo, Jinfang, Zhang, Jihong, Xu, Guoxiong, Chen, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5410245/
https://www.ncbi.nlm.nih.gov/pubmed/28186966
http://dx.doi.org/10.18632/oncotarget.15124