HMGB1 targeting by ethyl pyruvate suppresses malignant phenotype of human mesothelioma

Human malignant mesothelioma (MM) is an aggressive cancer linked to asbestos and erionite exposure. We previously reported that High-Mobility Group Box-1 protein (HMGB1), a prototypic damage-associated molecular pattern, drives MM development and sustains MM progression. Moreover, we demonstrated th...

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Detalles Bibliográficos
Autores principales: Pellegrini, Laura, Xue, Jiaming, Larson, David, Pastorino, Sandra, Jube, Sandro, Forest, Kelly H., Saad-Jube, Zeyana Salim, Napolitano, Andrea, Pagano, Ian, Negi, Vishal S., Bianchi, Marco E., Morris, Paul, Pass, Harvey I., Gaudino, Giovanni, Carbone, Michele, Yang, Haining
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5410252/
https://www.ncbi.nlm.nih.gov/pubmed/28186988
http://dx.doi.org/10.18632/oncotarget.15152

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5410252/
https://www.ncbi.nlm.nih.gov/pubmed/28186988
http://dx.doi.org/10.18632/oncotarget.15152

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