Therapeutically blocking interleukin-11 receptor-α enhances doxorubicin cytotoxicity in high grade type I endometrioid tumours

High grade type I endometrial cancers have poor prognosis. Interleukin (IL)11 is elevated in tumours and uterine lavage with increasing tumour grade in women. IL11 regulates cell cycle, invasion and migration and we recently demonstrated that IL11 receptor (R)α inhibition impaired low and moderate g...

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Detalles Bibliográficos
Autores principales: Winship, Amy, Van Sinderen, Michelle, Rainczuk, Katarzyna, Dimitriadis, Evdokia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5410257/
https://www.ncbi.nlm.nih.gov/pubmed/28186993
http://dx.doi.org/10.18632/oncotarget.15187

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5410257/
https://www.ncbi.nlm.nih.gov/pubmed/28186993
http://dx.doi.org/10.18632/oncotarget.15187

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