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Somatic molecular subtyping of prostate tumors from HOXB13 G84E carriers

A recurrent germline mutation (G84E) in the HOXB13 gene is associated with early onset and family history-positive prostate cancer in patients of European descent, occurring in up to 5% of prostate cancer families. To date, the molecular features of prostate tumors occurring in HOXB13 G84E carriers...

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Detalles Bibliográficos
Autores principales: Lotan, Tamara L., Torres, Alba, Zhang, Miao, Tosoian, Jeffrey J., Guedes, Liana B., Fedor, Helen, Hicks, Jessica, Ewing, Charles M., Isaacs, Sarah D., Johng, Dorhyun, De Marzo, Angelo M., Isaacs, William B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5410261/
https://www.ncbi.nlm.nih.gov/pubmed/28186998
http://dx.doi.org/10.18632/oncotarget.15196