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Mutations acquired by hepatocellular carcinoma recurrence give rise to an aggressive phenotype

Recurrence of hepatocellular carcinoma (HCC) even after curative resection causes dismal outcomes of patients. Here, to delineate the driver events of genomic and transcription alteration during HCC recurrence, we performed RNA-Seq profiling of the paired primary and recurrent tumors from two patien...

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Detalles Bibliográficos
Autores principales: Choi, Ji-Hye, Kim, Min Jae, Park, Yong Keun, Im, Jong-Yeop, Kwon, So Mee, Kim, Hyung Chul, Woo, Hyun Goo, Wang, Hee-Jung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5410272/
https://www.ncbi.nlm.nih.gov/pubmed/28038442
http://dx.doi.org/10.18632/oncotarget.14248