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Sepia ink oligopeptide induces apoptosis and growth inhibition in human lung cancer cells

Sepia ink oligopeptide (SIO), as a tripeptide extracted from Sepia ink, could be used as an inducer of apoptosis in human prostate cancer cells. We designed a cyclo-mimetic peptide of SIO by introducing a disulfide bond to stabilize the native peptide into beta turn structure, and produced a peptide...

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Detalles Bibliográficos
Autores principales: Zhang, Zhi, Sun, Lei, Zhou, Guoren, Xie, Peng, Ye, Jinjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5410297/
https://www.ncbi.nlm.nih.gov/pubmed/28423568
http://dx.doi.org/10.18632/oncotarget.15539