C-terminal truncated hepatitis B virus X protein regulates tumorigenicity, self-renewal and drug resistance via STAT3/Nanog signaling pathway

Hepatitis B virus (HBV) is a major risk factor of chronic liver disease and hepatocellular carcinoma (HCC). Random integration of HBV DNA into the host genome is frequent in HCC leading to truncation of the HBV DNA, particularly at the C-terminal end of the HBV X protein (HBx). C-terminally truncate...

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Detalles Bibliográficos
Autores principales: Ching, Rachel Hiu Ha, Sze, Karen Man Fong, Lau, Eunice Yuen Ting, Chiu, Yung-Tuen, Lee, Joyce Man Fong, Ng, Irene Oi Lin, Lee, Terence Kin Wah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5410322/
https://www.ncbi.nlm.nih.gov/pubmed/28186991
http://dx.doi.org/10.18632/oncotarget.15183

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5410322/
https://www.ncbi.nlm.nih.gov/pubmed/28186991
http://dx.doi.org/10.18632/oncotarget.15183

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