HRD1 sensitizes breast cancer cells to Tamoxifen by promoting S100A8 degradation

Estrogen receptor alpha positive (ER+) of breast cancer could develop resistance to antiestrogens including Tamoxifen. Our previous study showed that the E3 ubiquitin ligase HRD1 played an important role in anti-breast cancer. However, its role in chemotherapy resistance hasn't been reported. I...

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Detalles Bibliográficos
Autores principales: Wang, YanYang, Guo, AiBin, Liang, XiuBin, Li, Min, Shi, Ming, Li, Yan, Jenkins, Gareth, Lin, XiaWen, Wei, XueFei, Jia, ZhiJun, Feng, XueFeng, Su, DongMing, Guo, WanHua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5410327/
https://www.ncbi.nlm.nih.gov/pubmed/28423597
http://dx.doi.org/10.18632/oncotarget.15797

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5410327/
https://www.ncbi.nlm.nih.gov/pubmed/28423597
http://dx.doi.org/10.18632/oncotarget.15797

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