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Different prognostic impact of STK11 mutations in non-squamous non-small-cell lung cancer

STK11 is commonly mutated in lung cancer. In light of recent experimental data showing that specific STK11 mutants could acquire oncogenic activities due to the synthesis of a short STK11 isoform, we investigated whether this new classification of STK11 mutants could help refine its role as a progno...

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Detalles Bibliográficos
Autores principales: Pécuchet, Nicolas, Laurent-Puig, Pierre, Mansuet-Lupo, Audrey, Legras, Antoine, Alifano, Marco, Pallier, Karine, Didelot, Audrey, Gibault, Laure, Danel, Claire, Just, Pierre-Alexandre, Riquet, Marc, Le Pimpec-Barthes, Françoise, Damotte, Diane, Fabre, Elisabeth, Blons, Hélène
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5410347/
https://www.ncbi.nlm.nih.gov/pubmed/26625312
http://dx.doi.org/10.18632/oncotarget.6379