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Beneficial Effects of Sulforaphane Treatment in Alzheimer's Disease May Be Mediated through Reduced HDAC1/3 and Increased P75NTR Expression

Alzheimer's disease is an irreversible, progressive neurodegenerative disorder. The accumulation of Aβ in the brain is thought to play a causative role in the development of cognitive dysfunction in Alzheimer's disease. The p75 neurotrophin receptor is of great importance to protect agains...

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Detalles Bibliográficos
Autores principales: Zhang, Jingzhu, Zhang, Rui, Zhan, Zhipeng, Li, Xinhui, Zhou, Fuyuan, Xing, Aiping, Jiang, Congmin, Chen, Yanqiu, An, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5410605/
https://www.ncbi.nlm.nih.gov/pubmed/28507518
http://dx.doi.org/10.3389/fnagi.2017.00121