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Iron- and Hepcidin-Independent Downregulation of the Iron Exporter Ferroportin in Macrophages during Salmonella Infection

Retention of iron in tissue macrophages via upregulation of hepcidin (HAMP) and downregulation of the iron exporter ferroportin (FPN) is thought to participate in the establishment of anemia of inflammation after infection. However, an upregulation of FPN has been proposed to limit macrophages iron...

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Detalles Bibliográficos
Autores principales: Willemetz, Alexandra, Beatty, Sean, Richer, Etienne, Rubio, Aude, Auriac, Anne, Milkereit, Ruth J., Thibaudeau, Olivier, Vaulont, Sophie, Malo, Danielle, Canonne-Hergaux, François
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5410627/
https://www.ncbi.nlm.nih.gov/pubmed/28507548
http://dx.doi.org/10.3389/fimmu.2017.00498