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Tissue-protective activity of selenomethionine and D-panthetine in B16 melanoma-bearing mice under doxorubicin treatment is not connected with their ROS scavenging potential

AIM: To evaluate molecular mechanisms of tissue-protective effects of antioxidants selenomethionine (SeMet) and D-pantethine (D-Pt) applied in combination with doxorubicin (Dx) in B16 melanoma-bearing-mice. METHODS: Impact of the chemotherapy scheme on a survival of tumor-bearing animals, general ne...

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Detalles Bibliográficos
Autores principales: Panchuk, Rostyslav R., Skorokhyd, Nadia R., Kozak, Yuliya S., Lehka, Liliya V., Moiseenok, Andrey G., Stoika, Rostyslav S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Croatian Medical Schools 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5410729/
https://www.ncbi.nlm.nih.gov/pubmed/28409500
http://dx.doi.org/10.3325/cmj.2017.58.171