TLR ligands, but not modulators of histone modifiers, can induce the complex immune response pattern of endotoxin tolerance in mammary epithelial cells

Excessive stimulation of the TLR4 axis through LPS reduces the expression of some cytokine genes in immune cells, while stimulating the expression of immune defense genes during a subsequent bacterial infection. This endotoxin tolerance (ET) is mediated via epigenetic mechanisms. Priming the udder o...

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Detalles Bibliográficos
Autores principales: Günther, Juliane, Petzl, Wolfram, Zerbe, Holm, Schuberth, Hans-Joachim, Seyfert, Hans-Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2016
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5410871/
https://www.ncbi.nlm.nih.gov/pubmed/27913794
http://dx.doi.org/10.1177/1753425916681076

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5410871/
https://www.ncbi.nlm.nih.gov/pubmed/27913794
http://dx.doi.org/10.1177/1753425916681076

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