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Feasibility of multiplexed gene mutation detection in plasma samples of colorectal cancer patients by mass spectrometric genotyping

Mutation analysis of circulating tumor DNA (ctDNA) has recently been introduced as a noninvasive tumor monitoring method. In this study, we tested the mass spectrometric-based MassARRAY platform for multiplexed gene mutation analysis of plasma samples from colorectal cancer (CRC) patients. A total o...

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Detalles Bibliográficos
Autores principales: Shin, Su-Jin, Chun, Sung-Min, Kim, Tae-Im, Kim, Yu Jin, Choi, Hyun-Jeung, Jang, Se Jin, Kim, Jihun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5411034/
https://www.ncbi.nlm.nih.gov/pubmed/28459822
http://dx.doi.org/10.1371/journal.pone.0176340