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Gene expression patterns in the progression of canine copper-associated chronic hepatitis

Copper is an essential trace element, but can become toxic when present in abundance. The severe effects of copper-metabolism imbalance are illustrated by the inherited disorders Wilson disease and Menkes disease. The Labrador retriever dog breed is a novel non-rodent model for copper-storage disord...

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Detalles Bibliográficos
Autores principales: Dirksen, Karen, Spee, Bart, Penning, Louis C., van den Ingh, Ted S. G. A. M., Burgener, Iwan A., Watson, Adrian L., Groot Koerkamp, Marian, Rothuizen, Jan, van Steenbeek, Frank G., Fieten, Hille
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5411060/
https://www.ncbi.nlm.nih.gov/pubmed/28459846
http://dx.doi.org/10.1371/journal.pone.0176826