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Gene expression patterns in the progression of canine copper-associated chronic hepatitis
Copper is an essential trace element, but can become toxic when present in abundance. The severe effects of copper-metabolism imbalance are illustrated by the inherited disorders Wilson disease and Menkes disease. The Labrador retriever dog breed is a novel non-rodent model for copper-storage disord...
Autores principales: | Dirksen, Karen, Spee, Bart, Penning, Louis C., van den Ingh, Ted S. G. A. M., Burgener, Iwan A., Watson, Adrian L., Groot Koerkamp, Marian, Rothuizen, Jan, van Steenbeek, Frank G., Fieten, Hille |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5411060/ https://www.ncbi.nlm.nih.gov/pubmed/28459846 http://dx.doi.org/10.1371/journal.pone.0176826 |
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